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Vote for BestCrypt
With BestCrypt you can allocate a portion of free space on your hard drive where you keep all your sensitive data in encrypted form, creating a virtual drive in your system that you work with as you would any other drive. BestCrypt uses strong encryption algorithms, including Blowfish, GOST, and DES. Features include a time-out option, hot keys, a wiping utility, and the ability to add your own encryption algorithm. Windows NT/2000/XP are supported.